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Importantly, keratinocytes are not merely passive recipients of immune signals but actively shape the inflammatory milieu

2.1.3 Collapse of antioxidant defense mechanisms The antioxidant defense System in cells is critically dependent on glutathione peroxidase 4 (GPX4), a crucial metabolic enzyme that uses glutathione (GSH) to convert lipid peroxides into non-toxic alcohols, thereby minimizing harmful lipid peroxidation and safeguarding cells from ferroptosis

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Based on structural features, flavonoids are commonly categorized into several subgroups, including flavones, flavonols, flavanols, isoflavones, chalcones, etc

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