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Varicose Veins: Characterized by their enlarged and twisted appearance, varicose veins often cause discomfort and aesthetic concerns, making them a common target for sclerotherapy

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The treatment group showed significant reductions in body weight (approximately 5% loss) and white adipose tissue mass (35% reduction) compared to control animals, despite no changes in food intake

5-Amino-1MQ is a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the methylation of nicotinamide using S-adenosyl methionine (SAM)

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