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The M1 phenotype of microglia is responsible for synthesizing and releasing various cytokines, including prostaglandin E2 (PGE2), CRP, and TNF-alpha, into the bloodstream (Attwells et al., 2020)

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Acknowledgments We would like to thank the Director General of Health Malaysia for his permission to publish this article

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The SURMOUNT-1 data shows that weight loss continues in a roughly linear fashion through week 40, with the rate slowing gradually after that

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