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Clinica Chimica Acta

Activated STAT3 signaling pathway by ligature-induced periodontitis could contribute to neuroinflammation and cognitive impairment in rats

Chronic disease claims lack evidence

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

Each section was imaged at 12 focal planes, spaced 2 m apart, and the images were then stacked to create a composite for further analysis

Thermodynamic analyses using ESI-MS revealed that cellular copper transport follows a gradient of increasing binding affinity, with Cu + binding to GSH ( K d~10 13 M) at lower affinity than to dedicated copper chaperones such as antioxidant 1 copper chaperone (ATOX1), copper chaperone for superoxide dismutase (CCS), or cytochrome oxidase copper chaperone COX17 (COX17) 197