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Hypertension 71 , 12261238 (2018)

In a controlled study, healthy volunteers received a low dose of Escherichia coli endotoxin to induce experimental low-grade inflammation

PMID: 30090586 Heard KJ

By integrating transcriptomic and untargeted metabolomic analyses of BM neutrophils, we revealed a pivotal role for Chac2-driven GSH metabolic reprogramming in skewing neutrophils toward the N1 phenotype, which is orchestrated by upstream IFN-I signaling

NAD+ Supplies Needed Plan supplies based on a 100 mg SubQ dose 3x weekly using a 750 mg vial reconstituted with 7.5 mL BAC water (100 mg/mL)

doi: 10.3109/03602532.2011.558093