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Specifically, this meta-analysis combined the results of 19 clinical trials of vitamin E supplementation that mostly focused on secondary prevention and, as such, included subjects with pre-existing conditions, including heart disease, end-stage renal failure, and Alzheimer's disease

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BBA-Gen Subj 2017;1861:181324

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By contrast, the rotenone group demonstrated increased protein expression of cleaved-caspase-3 relative to the control group