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A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer: our experience in thyroid surgery

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180:E118-E125 Uchida W, Shibasaki K, Asano M, Takenaka T (1993) Antianginal effects of YM-16151-4 in various experimental angina models

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Inflammation upregulates hepcidin, promoting the internalization and degradation of the iron exporter ferroportin (FPN), thereby effectively blocking cellular iron efflux ( Clinical studies have confirmed that ferritin levels in GCF are significantly elevated in periodontitis patients and positively correlate with probing depth (PD) and clinical attachment loss (CAL) ( 2+ catalyzes the Fenton reaction, generating highly reactive hydroxyl radicals that provide the initial chemical driving force for the chain reaction of lipid peroxidation ( 2.2 Lipid metabolic reprogramming and lethal peroxidation execution The execution of ferroptosis is fundamentally driven by lethal peroxidation of membrane lipids, a process involving a series of active lipid metabolic reprogramming events