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These metabolites are likely required for energy substitutes, such as for gluconeogenesis and TCA cycle intermediates, but also for synthetic pathways, such as for protein and nucleic acid synthesis

Not surprisingly because of its stability, hydrophobic character, and small size, D-Nle- Tyr-ile-NH-(CH 2 )5-CONH 2 was predicted to be orally bioavailable

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When you swallow a standard pill, it must pass through the harsh environment of the stomach

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Hoffman-La Roche Ltd Basel, Switzerland This article was underwritten, in part, by a grant from Bayer Consumer Care AG, Basel, Switzerland