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A Novel Multikinase Inhibitor, Has Activity in Refractory AML, Including Transformed JAK2 Positive Myeloproliferative Disease (MPD), and in Philadelphi-Positive ALL

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Metabolomic investigations have demonstrated that even related species of lactic acid bacteria produce different levels of some small molecules (e.g., inosine and indole-3-lactic acid) that likely contribute to strain-specific antifungal activity against virulence factors (Spaggiari et al., 2024)