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Long-term studies demonstrate sustained improvements in physical capacity and metabolic function following senescent cell clearance, suggesting FOXO4-DRI treatment can fundamentally alter aging trajectories
In ARDS, an imbalance between these pathways contributes to exaggerated immune responses, tissue damage, and disease progression ( 2.1 Ferroptosis: a central player in ARDS pathogenesis Ferroptosis is a regulated, iron-dependent form of cell death distinguished by oxidative damage and lipid peroxidation
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ROS: Reactive oxygen species