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In: Walls RM, Hockberger RS, Gausche-Hill M, eds

Research suggests approximately 10-fold reduction in IGFBP affinity compared to native IGF-1

Available evidence is primarily observational or from cell culturenot conclusive for clinical outcomes

In 2010, about 34.1 million US adults over age 40 had myopia (NEI 2014)

This impairment of HDL function may contribute to lipid peroxidation of plasma lipoproteins, thereby fueling inflammation and promoting disease progression (62, 64)

Regardless of delivery route, clinical monitoring body composition, patient-reported outcomes, relevant laboratory markers is what confirms therapeutic effect