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Oral B12 supplementation is more accessible and cost-effective but relies on gastric intrinsic factor for absorption, rendering it unsuitable for individuals with gastric disorders or malabsorption syndromes

Chen Y, Zhang R, Wang L, Correa AM, Pataer A, Xu Y, Zhang X, Ren C, Wu S, Meng QH, Fujimoto J, Jensen VB, Antonoff MB, Hofstetter WL, Mehran RJ, Pisimisis G, Rice DC, Sepesi B, Vaporciyan AA, Walsh GL, Swisher SG , Roth JA, Heymach JV, Fang B

Rafii MS, Tuszynski MH, Thomas RG, Barba D, Brewer JB, et al

While some patients have complete or near-complete symptom resolution after surgery, others have poor outcomes including persistent pain (even if the bladder is removed), complications or new symptoms with lifelong significant bother

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