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the peptide is used as a molecular probe rather than for defined physiological outcomes

The increased lipolysis by isoproterenol alone (in the absence of co-treatment with insulin) in Insr P1195L/ +/HFD adipocytes also suggests that some factors [such as activities of perilipin 9 and/or adipocyte triglyceride lipase 10 (ATGL)] other than insulin-dependent suppression of phospho-HSL may contribute to the increased lipolysis 11

Feb 2009;181(2):741-51

But when you go that unproven route, theres a bigger risk of missing the underlying cause and suffering side effects

It means the why matters