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doi: 10.3389/fped.2017.00121 13 Centers for Disease Control and Prevention

Both act through the ghrelin/GHSR pathway, but Ipamorelin is generally discussed as more selective, while GHRP-6 is an older GH-releasing peptide often associated with appetite-related signaling

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Suppah M, Kamal A, Saadoun R, et al

DSIP is remarkably well-tolerated with minimal side effects when used under proper medical supervision with appropriate dosing protocols

Though the raw building blocks (like acrylic acid) can be irritating on their own, cosmetic-grade versions go through purification to keep levels extremely low