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Further studies in the 2000s, (7) suggested that the GHK-Cu peptide hosts the potential to not only stimulate the collagen synthesis but also stimulate the production of tissue inhibitors, TIMP-1 and TIMP-2

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Here, we only focus on the mechanisms of cytotoxic stadium of the brain edema, which is related to the increased glutamate levels and the impaired glutamate uptake

The mechanism involves modulation of dopamine and serotonin systems alongside promotion of nerve growth factor