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(31) highlighted that endothelial cell, comprising the single-layer epithelium of the vascular system, play crucial roles in maintaining intravascular homeostasis
In their 2014 lung cancer study they also found that antioxidant supplements caused lung tumor cells to turn off the activity of a well-known cancer-suppressing gene called p53
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On the other hand, exosomes from cells with reparative potential, such as bone marrow mesenchymal stem cells (MSCs) or amniotic epithelial cells, have been found to downregulate the pro-ferroptotic lipid metabolism enzyme ACSL4, or upregulate parallel anti-ferroptosis pathways like FSP1/GPX4, thereby attenuating ferroptosis and promoting cartilage repair (Wang Y
