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Following age adjustment, 219 of the 267 metabolites remained significantly associated with methylmalonic acidemia (MMA), as detailed in Table S2

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Ferrostatin-1 prevents A-like aggregates, reduces lipid peroxidation and boosts the expression of iron storage in AD-cBOs Interestingly, A-like aggregates were observed in 50-days-old AD brain organoids compared to isogenic brain organoids (Fig