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However, relying on enemas may make it more difficult for a person to have an unaided bowel movement in the future

For example, carvacrol upregulates GPX4 expression to slow the progression of lipid peroxidation, thereby inhibiting ferroptosis and showing potential for treating cerebral ischemia [124]

Acetaminophen (paracetamol), once widely used for OA-related pain, is now considered a second-line agent due to its modest analgesic efficacy and potential for hepatotoxicity at higher doses

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Week 12+: At maintenance doses, appetite suppression tends to stabilize

The second step is catalyzed by GSH synthase, which adds glycine to -glutamylcysteine to form -glutamylcysteinylglycine or GSH