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B12 injections may help lower levels of homocysteine, an amino acid that, when elevated, can be a risk factor for heart disease and stroke

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When deficiency is diagnosed, lifelong B replacement is often required (especially in pernicious anemia)

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Epigenetic Regulation and Longevity Implications : Through its role in SAM recycling and methylation balance, 5-Amino-1MQ influences epigenetic pathways linked to energy metabolism and aging