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In the rat liver ischemia-reperfusion injury model and hepatocyte HL-7702 experiments, catalpol upregulated miR-410-3p, inhibiting the activation of the TLR4/High Mobility Group Box 1 (HMGB1) signaling pathway, alleviating aseptic inflammation in rat liver tissue, and inhibiting oxidation, thus providing protection against ischemia-reperfusion injury (Wang, 2023

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