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The ITS formulation exemplifies this duality: insulin activates insulin and IGF 1 receptors to drive metabolic and proliferative pathways

doi:10.1073/pnas.1222798110

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When it quenches a free radical, it becomes oxidized and cannot quench more free radicals until it is converted back to its reduced form by special enzymes

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The filters were treated with anti-fade solution Citifluor AF1 (Sigma-Aldrich ) and viewed using a Leica fluorescent microscope at 40 magnification