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In this study, we developed a new molecule JMF4073, which inhibits both thymidylate kinase (TMPK) and cytidylate kinase (CMPK)

Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM (2015) An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis

This dose was chosen rather than the 3 mg/kg starting dose used in rheumatoid arthritis (RA) as it was felt that PsA, a spondyloarthropathy, might respond better to the dosing used in irritable bowel disease (IBD), which shares some genetic and possible pathophysiologic characteristics

Int J Phytoremediation 18(2):200209

Christopher Chang

Am J Clin Dermatol 25 , 891908 (2024)