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(2) the ability of the TJ to selectively allow paracellular transport of certain ion species acting as ion channel and (3) the ability of the TJs to maintain cell polarity, by blocking the free diffusion of proteins and lipids between the apical and basolateral domains of the plasma membrane

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Because these processes are connected to connective tissue repair and structural tissue maintenance, the peptides are sometimes explored in models related to muscle biology, tendon and ligament signaling, and recovery-related cellular responses

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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Courtine G, Song B, Roy RR, Zhong H, Herrmann JE, Ao Y, et al