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The PXR-SHP-CYP7A1 signaling pathway showed a new potential in increasing BA synthesis and promoting cholesterol consumption

NAD+ homeostasis in health and disease

Sterility Testing (USP ) - Are there viable microorganisms present that could compromise the material

Gene expression modulation studies (over 4,000 human genes documented)

all authors contributed to the interpretation of the results

Thus, we set out to determine, first, whether Kat6a +/ mice could be used as a model for ARTHS with respect to effects on histone acetylation and cognitive and social functions and, second, whether treatment aimed to increase histone acetylation levels might ameliorate any learning, memory, or social dysfunction that might be present