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Consistent with their functional importance, individual mutation of these residues to either glycine or alanine reduced the association of SNIP1 with the activated spliceosome, and the K265G single mutant as well as the K265G/K301G double mutant caused defects in pre-mRNA splicing and cell proliferation

Rogovskii V

Pharmaceuticals (Basel)

Secondary antioxidants are externally provided from dietary sources, such as vitamins (vitamins A, C and E), minerals (selenium, zinc, copper and manganese) and other substances, including polyphenols found in grapes and green tea

A.GarlandL.et al

10.1046/j.1471-4159.2001.00383.x J