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Diet-induced microbial dysbiosis alters the composition and metabolic function of gut bacteria, reducing the production of beneficial metabolites such as SCFAs and increasing the generation of harmful compounds like LPS and TMAO

In DKD patients, gemigliptin treatment significantly suppressed the expression of renal tubular injury biomarkers and the levels of vascular calcification markers (187)

No serious adverse events were reported, indicating a favorable safety profile for this combination approach (272)

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[Google Scholar] 56.Bartlett DL, Carr BI, Marsh JW

In some embodiments, the formulation or composition comprises between about 0.01% to about 80% by weight of the viscosity modulating agent