By further lowering the pH value or increasing the reaction time, the complete decomposition of DOX@COF could be achieved in PBS, resulting in the complete release of DOX and demonstrating pH response characteristics
It is primarily used as a research tool to explore age-related cellular pathways and compare experimental outcomes across conditions
It is hard to explain how the same lab on multiple occasions over a decade or so can publish multiple pieces of data that other labs cant reproduce. Whats more, GlaxoSmithKline halted a Sirtris trial in humans because of potential negative side effects and then shut the company down altogether just five years after buying it
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G.MatsacosD.SimP.CluneE.MustafaT.et al (2001)
Storage conditions must be kept optimum to keep it stable and sterile