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LW: Conceptualization, Writing review & editing

A BCB4 variant is associated with hepatobiliary MR abnormalities in people with low-phospholipid-associated cholelithiasis syndrome

Microglia exhibiting neuroinflammatory signatures expanded with disease progression (such as GPNMB, THEMIS, PVALB , and WIF1 )

Reduces Dark Circles: brightens dark areas around the eyes

For native IGF-1, binding to IGFBP-3 and ALS lengthens circulating half-life the ternary complex protects the peptide from rapid renal clearance and proteolysis, so bound native IGF-1 persists in blood for hours rather than the roughly 10 minutes reported for free IGF-1

Statements Data availability statement The datasets presented in this article are not readily available because the article contains complete data used to support the findings of this study