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developed a drug-delivery system loaded with temozolomide based on porous silicon NPs to improve the survival of mice with glioma

doi: 10.1016/j.jtemb.2019.126435 256

However, with increasing doses of acetaminophen, there is progressive dislocation of nuclear translocation, transcription, translation and protein activity as the rate of drug bioactivation over-whelms cell defence through the destruction of crit-ical proteins at least 31 of these critical proteins have been identified (Park et al ., 2005)

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Xu L, Liu Y, Sun Y, et al