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Integrative Medicine: A Clinicians Journal, 13(1), 812

Conversion of cholecalciferols to calcidiol is dependent solely upon substrate availability as there is no regulatory mechanism to control the formation of calcidiol

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Zhao Y et al (2019) The clinical outcomes of selenium supplementation on critically ill patients: a meta-analysis of randomized controlled trials

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To overcome this technical limitation, we utilized the alkylating agent n-ethylmaleimide (NEM) 53 to stabilize thiol containing metabolites