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Vitamin B12 helps to: Maintain normal brain and nervous system function

Vitamin B12 is an essential nutrient that plays a key role in many bodily functions, including energy production, DNA synthesis, and nerve cell health

The nitric oxide modulation extends beyond blood vessel formation to direct anti-inflammatory effects

By preventing NFB from entering the cell nucleus, it reduces production of proinflammatory signals including TNF, IL1, IL6, and IL12

Since then, many different concepts and definitions have been proposed