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The drug was generally well tolerated, with the most common side effects being mild to moderate gastrointestinal issues such as nausea, vomiting, diarrhea, and constipation

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This protocol rapidly induced marked functional disability, in particular, a difficulty with maintaining body balance while rearing, an inability of the right forelimb to react (and thereby cuprizone-rats react only with one or no forelimb), and severely affected various brain areas [31]

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doi: 10.1016/0024-3205(94)00796-9

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