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Molecular biology insights reveal that fatigue also induces changes in gene expression and protein synthesis within muscle cells

SULT1A1 also takes part in transformation of hydroxymethyl polycyclic aromatic hydrocarbons, hydroxyderivatives of arylamines, allylic alcohols and heterocyclic amines to their reactive intermediates which are able to bind to nucleophilic structures such as DNA and consequently act as mutagens and carcinogens (Glatt et al., 2001)