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To determine if the presence of low concentrations of tamoxifen causes a differential increase of ROS levels in CHO R C5 versus AuxB1, cells were exposed for 24 h to tamoxifen (1 M and 5 M) and intracellular ROS was quantified using 2',7'-dichlorodihydrofluorescein diacetate (H 2 DCFDA) dye [38]

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mild brightness noted within a week

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