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Batch reproducibility, stability, quality control matter

A 2017 meta-analysis of data from 15 trials, including more than 71,000 participants at risk of or with existing CVD, showed that B-vitamin supplementation had no significant effect on risk of myocardial infarction (heart attack) or all-cause mortality but reduced risk of stroke by 10% (RR, 0.90

The effects depend on individual deficiency levels and lifestyle

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[DOI] [PMC free article] [PubMed] [Google Scholar] Zhang X, Liu B, Lal K, Liu H, Tran M, Zhou M, et al

Blood-brain barrier leakage is increased in parkinsons disease