presented a pH/reduction-sensitive carboxymethyl chitosan nanogel (CMCSN) modified by targeting peptide angiopep-2 (ANG) and loading with doxorubicin (DOX) named DOX-ANG-CMCSN
This creates a dangerous cycle: toxin buildup increases oxidative stress, which further depletes glutathione, making detoxification even less efficient
PMID: 15666314 Bker T, Vanem TT, Pripp AH, Rand-Hendriksen S, Paus B, Smith HJ, Lundby R
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Adaptation strategies of two closely related Desmodesmus armatus (green alga) strains contained different amounts of cadmium: a study with light-induced synchronized cultures of algae