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Summary and prospect With the discovery that FSP1 can regulate ferroptosis independent of GPX4, researchers have become more enthusiastic about finding GPX4-independent ferroptosis pathways

Trends Pharm Biotechnol

3-PLG-dopa-A-GSH) and ibuprofen-coupled (3-PLG-ibu

4-HNE is involved in PD pathology by covalently modifying -syn to promote its aggregation, disrupting the ubiquitin-proteasome system, and interfering with dopamine receptor function, and has been found to alter dopamine transport, contributing to dopamine loss (82, 86, 88)

doi: 10.3389/fimmu.2017.01239 66 DjukicT.StevanovicG.CoricV.BukumiricZ.Pljesa-ErcegovacM.MaticM.et al

The future of precision lipidology will depend on outcome evidence