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(7.1) Bleomycin: Ascorbic acid and riboflavin may reduce the activity of bleomycin

Fuxe et al., 2010)

C (101 MHz, CDCl 3 ) 171.09 (C), 134.80 (t, J = 23.8 Hz, CD), 133.12 (td, J = 24.8, 9.9 Hz, CD), 130.22 (td, J = 24.7, 12.5 Hz, CD), 117.87 (d, J = 85.8 C), 38.67 (CH 2 ), 38.37 (CH 2 ), 27.54 (CH 2 ), 26.86 (d, J = 16.7 Hz, CH 2 ), 22.31 (d, J = 51.3 Hz, CH 2 ), 21.72 (d, J = 4.3 Hz, CH 2 )

The desired concentration of the peptide can be achieved by adjusting the amount of solvent added

Route dramatically changes exposure and relevance

Standard oral glutathione has very low absorption rates, while liposomal delivery is designed to bypass digestive breakdown and support cellular uptake