Untargeted LCMS/MS metabolomics identified 46 differentially regulated metabolites spanning sugars, amino acids, organic acids, glucosinolates, and phenolics
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Moreover, combining CD300ld knockout with anti-PD1 therapy produced a synergistic effect, resulting in robust tumor regression, far exceeding the efficacy of either treatment alone [111]
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Thus, astrocytes represent an excellent model to investigate GSH production due to their higher GSH levels and enzymatic efficiency
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