For systemic or gut-related protocols, abdominal subcutaneous injection is the standard approach
However, as with any supplement or treatment, there's potential for side effects, especially when B12 is given in very high doses
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Foundational mouse study (Baar et al., 2017, Cell) Designed FOXO4-DRI and showed selective senescent-cell clearance, with restored fitness, fur density, and kidney function in aged and chemotherapy-treated mice
Consult a healthcare professional before use if pregnant, nursing, taking medication, or have a medical condition
Standard assays of GST activity The activities of the GST stocks were assayed at 30 C with the standard substrates, 1 mM CDNB (stock solution in ethanol) and 1 mM GSH in 0.1 M sodium phosphate buffer pH 6.5, containing 1 mM EDTA, and the formation of the product S-2,4-dinitrophenyl-glutathione (DNP-SG) was followed spectrophotometrically at 340 nm 23