This gelatin is the hallmark of a bone broth rich in collagen, providing essential and non-essential amino acids
Immunological mechanisms The role of immune system in xenobiotics-induced hepatotoxicity is discussed in previous investigations.55 Immune-mediated reactions are suggested to play a role in antithyroid drug-induced hepatotoxicity.56 Although the mechanism(s) underlying this event is not fully elucidated yet 56, but cytokines are thought to play a role in immunemediated liver injury caused by methimazole.56 Cytokines could play an important role in DILI.57,58 Hence, another possible mechanism(s) for antithyroid drugsinduced hepatotoxicity could be immune system-mediated
503 Neutrophils, another key player in liver regeneration, are also influenced by cholesterol metabolism
Additionally, altered calcium signaling may play a role in defective endolysosomal trafficking, further affecting cellular homeostasis [146]
Lactobacillus acidophilus La-14 (SD-5212) and Bifidobacterium longum subsp
Kudos to the industry sponsor of this study for supporting the double-blind design, because it removed a significant potential bias that might have otherwise tainted the results
