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Key candidates include HOMA-IR to assess insulin resistance, serum testosterone and sex hormonebinding globulin (SHBG) for androgen excess, anti-Mllerian hormone (AMH) to reflect ovarian reserve and follicular activity, and inflammatory cytokines such as TNF- and IL-6

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The significant increase in ENZ release with increasing GSH or DTT concentrations supports the disulfide bond cleavage mechanism

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