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It also minimizes the risk of introducing particulates or microorganisms that could interfere with downstream laboratory analyses

These amounts are considered safe because the human body, as a general matter, can safely store from 1,000 to 2,000 times the RDA, without negative consequence (anything more will generally be excreted in urine, per NCBI Bookshelf)

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Just like humans, dogs also need vitamin b12 to remain healthful and active