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Other lipotropics include choline, inositol, and betaine (trimethylglycine), all of which help prevent the accumulation of fat in the liver and thus ensure normal liver function, which is essential for the elimination of toxins from the body

Triggering oxidative stress , producing free radicals that inflame tissues

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Cell J 17(3):412421 Mueller E (2014) Understanding the variegation of fat: novel regulators of adipocyte differentiation and fat tissue biology

Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

Ultimately, these approaches could be employed together