Subgingival dental plaque is the main etiological agent for initiating inflammatory changes in the periodontal tissue and the cell component of bacteria, which exist in the dental plaque and recruit and activate hyper-responsive polymorphonuclear leukocytes (PMNs), which are innate immune cells that may play both defensive and destructive roles in periodontitis (Nicu and Loos, 2016) and accelerate oxidative stress biomarkers (Ademowo et al., 2020)
doi: 10.5409/wjcp.v13.i3.94721
Improving insulin resistance and blood sugar: Modulates cytokines from adipose tissue, potentially useful as an anti-obesity functional food ingredient [11]
Oral formulations exist, though most clinical protocols use subcutaneous injection because it delivers more predictable dosing
However, oral administration of GSH does not efficiently increase circulating levels of GSH 24,25,26
Front Endocrinol (Lausanne) 14:1138245