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Using an alternative strategy, targeting tumor endothelium and TEM8-positive malignant cells by employing TEM8-specific CAR T cells was effective in treating triple negative breast cancer (TNBC) patient derived xenograft (PDX) models and metastatic TNBC cell-line xenografts [324]

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The recent 16-week study positions Petrelintide as a potential best-in-class amylin analog, showing impressive weight loss results comparable to well-established GLP-1 receptor agonists

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