Our team and others have successfully demonstrated that GPER modulates nutrient metabolism, spanning glucose, protein, and lipid metabolism, while also contributing to vitamin and mineral metabolism
2BlackfordMGFelterTGothardMD
In the process of purine synthesis, 5-phosphoribosyl--pyrophosphate (PRPP) generated from the pentose phosphate pathway (PPP) is converted to phosphoribosyl--amine (PRA) through the action of phosphoribosyl pyrophosphate amidotransferase (PPAT) when an amide group from glutamine is introduced
It has been suggested that S-palmitoylation of PMPsincluding G subunitsoccurs exclusively at the Golgi, an event followed by their transport to the PM via the secretory pathway 12
Targeting the NLRP3 inflammasome in inflammatory diseases
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