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Oral trehalose added to drinking water has been shown to increase autophagy, reduce damage to substantia nigra dopaminergic neurons, and promote the nuclear translocation of Nrf2 and the expression of downstream antioxidant enzymes [115]

The evidence as presented provides the rationale to further investigate this naturally occurring peptide in preclinical and clinical aging studies

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Lh (trp8arg/ile15thr), lhr (inslq) and fshr (asn680ser) polymorphisms genotypic prevalence in women with endometriosis and infertility