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2 O 2 was not affected, unlike GCL ( FIGURE 3 Concerning GCL, while two disulfides bonds (Cys186Cys406 and Cys349Cys364, Arabidopsis GCL numbering) are present in orthologs from Rosids, only the first one is involved in the redox modulation of the enzyme activity ( A

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8 Conclusion PCOS is fundamentally characterized by interconnected pathological axes encompassing dysregulated glucose-lipid metabolism (manifesting as IR and obesity), HA, chronic inflammation with oxidative stress, and ovulatory dysfunction