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Ethanol (2 mL/kg) was orally administered to the mice 30 min before receiving the test compounds (200 mg/kg), and the behavioral and oxidative stress-related biochemical parameters altered by ethanol were analyzed

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As demonstrated in 1 H-NMR of CDs reduced by NaBH 4 (CDs-NaBH 4 ), a significant increase of the peaks in the region of 1.02.0 ppm was observed, indicating that the C=O of CDs was reduced to C-O, respectively (Figure 5D)